A Randomized Controlled Trial of Non-intubated Versus Intubated VATS for Mediastinal Neoplasm
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
In recent year, non-intubated anesthesia had emerged as an available and promising alternative for thoracic procedure. However, its safety and feasibility in video-assisted thoracoscopic surgery (VATS) for mediastinal neoplasm remain controversial. This randomized controlled trial is designed to evaluate the impact of the non-intubated approach on surgical and perioperative outcomes in patients undergoing mediastinal neoplasm resection.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:
• Mediastinal neoplasm was diagnosed by chest enhanced CT
• The patients with age ≥ 18 and ≤ 80 years old
• The patients whose tumor diameter was \<6 cm
• ASA grade: I-III
• The patients should understand the research and sign the informed consent
Locations
Other Locations
China
the First Affiliated Hospital of Guangzhou Medical University
RECRUITING
Guangzhou
Contact Information
Primary
Shuben Li, Deputy Director
13500030280@163.com
86(020) 8306 2114
Time Frame
Start Date: 2025-03-26
Estimated Completion Date: 2028-08-31
Participants
Target number of participants: 132
Treatments
Experimental: Non-intubated group
Patients received tubeless VATS for mediastinal neoplasm
Active_comparator: Intubated group
Patients received VATS mediastinal neoplasm resection under intubated general anesthesia.
Related Therapeutic Areas
Sponsors
Collaborators: The First Affiliated Hospital of Guangzhou Medical University
Leads: Shuben Li