The Adult Hemorrhagic Moyamoya Surgery Study
The aim of this study is to investigate whether extracranial-intracranial(EC-IC) bypass surgery could prevent rebleeding and improve neurological function in adult moyamoya with hemorrhagic onset.
• Independent in activity of daily living(The modified Rankin Scale 0-2)
• At least one month since the most recent hemorrhagic stroke
• The neurological deficit must be stable for more than 6 weeks
• Bleeding in ventricle,cortex,basal ganglia,thalamus and subarachnoid space confirmed by computed tomography plain scan
• Digital substraction angiography demonstrating progressive stenosis or occlusion in the terminal portion of the internal carotid artery and/or the initial portion of the anterior or middle cerebral arteries
• Digital substraction angiography demonstrating formation of abnormal collateral networks(moyamoya vessels) at the base of the brain,mainly in the region of thalamus and basal ganglia
• Digital substraction angiography demonstrating the vasculopathy appeared unilaterally or bilaterally
• Competent to give informed consent
• Accessible and reliable for follow-up