Multicentric Randomized Prospective Study Assessing the Impact of the Bougie Calibration Size During Laparoscopic Sleeve Gastrectomy on the Rate of Postoperative Staple-line Leak Rate

Status: Recruiting
Location: See all (12) locations...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Staple-line leak is the most frequent and incapacitating complication after laparoscopic sleeve gastrectomy (LSG). The aim of this prospective randomized trial is to compare the staple-line leak rate after LSG according to the use of a standard bougie calibre (34, 36 or 38 Fr) or 48-Fr, assuming that a higher diameter is correlated with a lower risk of leak, without lowering long-term weight loss.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: f
View:

• Patients between 18 and 70 years

• Sleeve gastrectomy as a primary bariatric procedure

• Body Mass Index (BMI) \> 40 kg/m² or \> 35 kg/m² associated with at least one comorbidity susceptible to improve after surgery (including arterial hypertension, obstructive sleep apnea syndrome and other severe respiratory disorders, severe metabolic disorders, particularly type 2 diabetes, incapacitating osteo-articular disorders, non alcoholic steatohepatitis)

• Decision for intervention after multidisciplinary discussion

• Written informed consent

Locations
Other Locations
France
Hôpital Ambroise Paré
SUSPENDED
Boulogne-billancourt
Hôpital Côte de Nacre CHU de Caen
WITHDRAWN
Caen
CHU Antoine Béclère
RECRUITING
Clamart
Centre hospitalier Intercommunal de Créteil
WITHDRAWN
Créteil
Hôpital MICHALLON, CHU de Grenoble
WITHDRAWN
La Tronche
Hôpital Dupuytren - Limoges
WITHDRAWN
Limoges
Clinique de l'Yvette
RECRUITING
Longjumeau
Service de chirurgie générale et digestive, œsogastrique et bariatrique - Hôpital Bichat
RECRUITING
Paris
CHI - Centre Hospitalier Poissy/Saint-Germain-en-Laye
RECRUITING
Poissy
CH Saint-Denis
RECRUITING
Saint-denis
Clinique Mutualiste Chirurgicale
WITHDRAWN
Saint-etienne
Hôpitaux de Brabois
RECRUITING
Vandœuvre-lès-nancy
Contact Information
Primary
Hadrien TRANCHART, Dr
hadrien.tranchart@aphp.fr
(+33)145374037
Backup
Ibrahim DAGHER, Pr
ibrahim.dagher@aphp.fr
(+33)145374143
Time Frame
Start Date: 2020-10-08
Estimated Completion Date: 2027-09-08
Participants
Target number of participants: 1658
Treatments
Experimental: Laparoscopic sleeve gastrectomy using 48-Fr bougie
Patients will undergo laparoscopic sleeve gastrectomy with a 48-Fr (16 mm) bougie
Active_comparator: Laparoscopic sleeve gastrectomy using standard care bougie
Patients will undergo laparoscopic sleeve gastrectomy with a standard care bougie (34, 36 or 38-Fr)
Related Therapeutic Areas
Sponsors
Leads: Assistance Publique - Hôpitaux de Paris

This content was sourced from clinicaltrials.gov