Tailoring One-Anastomosis Gastric Bypass Based on Total Small Bowel Length - A Randomized Controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

One Anastomosis Gastric Bypass (OAGB) is the most common metabolic and bariatric surgery (MBS) in Israel, recognized for its effectiveness in achieving sustainable weight loss and mitigating obesity-related diseases. The metabolic outcomes of OAGB are significantly influenced by the length of the biliopancreatic limb (BPL). The objective of this study is to determine whether tailoring the BPL length to the total small bowel length (TSBL) results in more effective weight loss compared to patients undergoing OAGB with a fixed BPL of 180 cm. Efficacy and safety of this approach will also be evaluated, ensuring it does not lead to long-term morbidity or negatively impact patients' quality of life.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Adults (≥18 years) undergoing OAGB

Locations
Other Locations
Israel
Tel Aviv Sourasky Medical Center
RECRUITING
Tel Aviv
Contact Information
Primary
Adam Abu-Abeid, M.D
adama@tlvmc.gov.il
+972524266283
Time Frame
Start Date: 2025-01-29
Estimated Completion Date: 2029-01-31
Participants
Target number of participants: 500
Treatments
Active_comparator: Control group BPL 180 cm
Total bowel length measure and BPL will be 180 cm regardless of total small bowel length
Experimental: Tailored BPL length
Total bowel length measure and BPL will be 40% of total bowel length ensuring at least 250 cm common channel
Related Therapeutic Areas
Sponsors
Leads: Tel-Aviv Sourasky Medical Center

This content was sourced from clinicaltrials.gov