Randomized Comparison of HARVesting the Left Internal Thoracic Artery in a Skeletonized Versus Pedicled Technique: the HARVITA Trial

Status: Recruiting
Location: See all (8) locations...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Internal thoracic arteries can be harvested in skeletonized or pedicled technique. Latest research has posed a potential adverse effect of skeletonizing the internal thoracic arteries on graft patency rates and clinical outcome. Prospective, randomized, multi-centre trials are necessary to investigate the impact of harvesting technique of left internal thoracic artery (LITA) on graft patency rates and clinical outcome after coronary artery bypass grafting. The HARVITA trial compares skeletonized and pedicled harvesting technique of LITA regarding graft patency rates and patient survival.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• Primary isolated CABG patients with multi-vessel disease (defined as ≥70 % stenosis of the left anterior descending artery (LAD) and ≥50% stenosis of circumflex and right coronary territory, with or without a ≥50% stenosis of the left main artery).

Locations
Other Locations
Austria
Medical University of Graz
NOT_YET_RECRUITING
Graz
Medical University of Innsbruck
RECRUITING
Innsbruck
Medical University of Vienna
NOT_YET_RECRUITING
Vienna
Germany
University of Duisburg-Essen
NOT_YET_RECRUITING
Essen
University of Freiburg
NOT_YET_RECRUITING
Freiburg Im Breisgau
University Hospital Gießen
NOT_YET_RECRUITING
Giessen
University of Jena
NOT_YET_RECRUITING
Jena
Switzerland
University Hospital Bern
NOT_YET_RECRUITING
Bern
Contact Information
Primary
Hannes Abfalterer, Dr. med. univ.
hannes.abfalterer@i-med.ac.at
004351250482988
Time Frame
Start Date: 2024-03-12
Estimated Completion Date: 2031-10-01
Participants
Target number of participants: 1350
Treatments
Active_comparator: skeletonized harvesting technique
In skeletonized harvesting technique, only the left internal artery itself is harvested.
Active_comparator: pedicled harvesting technique
In pedicled harvesting technique the left internal thoracic artery, it's accompanying veins and parts of the endothoracic fascia is harvested, creating a 1-2 cm broad pedicle.
Sponsors
Leads: Medical University Innsbruck

This content was sourced from clinicaltrials.gov