No-Touch Saphenous Venous Harvesting TechniQue versUs Radial artEry in Coronary Artery Bypass Grafting in womEN: The QUEEN Multicenter Randomized Controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The use of a graft from the left internal thoracic artery to the left anterior descending artery has become the gold standard for the indication of coronary artery bypass grafting. However, choosing a graft for the second-best coronary artery, focusing on long-term patency, is still a challenge. The saphenous vein using the no-touch technique is an alternative to a radial artery graft, but there is little evidence, especially in women. This randomized clinical study aims to compare the patency of these grafts in the second-best coronary artery in women undergoing coronary artery bypass grafting.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:

• Women aged 18 years or older and younger than 75 years, undergoing isolated and primary myocardial revascularization surgery, with triarterial coronary artery disease (three vessels involved) in vessels subject to surgical revascularization and left ventricular ejection fraction greater than 35%. The target coronary vessels of the study will be those in the territory of the left circumflex artery and the right coronary artery, which must have at least 1.5 mm in diameter, and with proximal obstructive lesions of at least 70%.

Locations
Other Locations
Brazil
Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina de São Paulo
RECRUITING
São Paulo
Contact Information
Primary
Omar A V Mejia, MD, PhD
omarvmejia@incor.usp.br
+551126615014
Backup
Leonardo L Lacava, MD
lacavalopes@hotmail.com
+55 49 33224453
Time Frame
Start Date: 2024-01-01
Estimated Completion Date: 2027-12-30
Participants
Target number of participants: 150
Treatments
Other: Radial - Anterolateral / Saphenous - RCA
Radial artery graft for the anterolateral wall, and no-touch saphenous vein graft for the right coronary artery territory
Other: Radial - RCA / Saphenous - Anterolateral
Radial artery graft for the territory of the right coronary artery and no-touch saphenous vein for the anterolateral wall.
Sponsors
Leads: University of Sao Paulo General Hospital
Collaborators: Hospital Norte Paranaense, Hospital Unimed João Pessoa, Hospital do Coração Alagoano Prof. Adib Jatene, Instituto Nacional de Cardiologia, Hospital Hernan Henriquez Aravena

This content was sourced from clinicaltrials.gov