Heart Bypass Surgery Clinical Trials

Clinical trials related to Heart Bypass Surgery Procedure

Effect of Non-anemic Iron Deficiency on Outcome Following Off-pump Coronary Revascularization

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

This is a single center retrospective study of patients who underwent off pump coronary artery bypass surgery between 2016.11\ 2023.05. From this patient group, preoperatively non-anemic patients were selected and were divided into 2 cohorts according to their preoperative iron status; iron replete and iron deficient. These two cohorts were compared to evaluate the effect of preoperative iron deficiency on patient outcomes. The primary end point was the occurrence of composite morbidity/mortality end points which were: in hospital mortality, acute kidney injury (AKI), stroke, deep sternal infection, hemostatic reoperation, prolonged mechanical ventilation of more than 24hours, delirium and postoperative myocardial infarction. Occurrence of any one of these outcomes counted as primary end point met. Secondary outcome was to evaluate and compare hemoglobin recovery of iron replete and deficient patients until one year after surgery.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 29
Maximum Age: 85
Healthy Volunteers: f
View:

• Patients who received off pump coronary artery bypass surgery (OPCAB) between 2016.11.01-2023.05.31

Locations
Other Locations
Republic of Korea
Yonsei University Health system, Severance Hospital
RECRUITING
Seoul
Time Frame
Start Date: 2016-11-01
Estimated Completion Date: 2024-05-31
Participants
Target number of participants: 433
Treatments
Iron replete
Patient who did not meet the criteria for iron deficiency (see below)
Iron deficient
patients with preoperative iron profile of either of the following were defined as iron deficient:~1. serum ferritin \<100mcg/L~2. 100mcg/L \< serum ferritin \<300mcg/L and~ * transferrin saturation \< 20% or~ * C reactive protein ≥ 5mg/L
Sponsors
Leads: Yonsei University

This content was sourced from clinicaltrials.gov