Non-invasive Detection of Acute Cell-mediated Graft Rejection in Pediatric Heart Transplant Recipients: the Role of Cardiovascular Magnetic Resonance
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
Acute cardiac rejection is currently diagnosed by endomyocardial biopsy (EMB), but multiparametric cardiac magnetic resonance (CMR) may be a non-invasive alternative by its capacity for myocardial structure and function characterization. Our primary aim was to determine the utility of multiparametric CMR in identifying acute graft rejection in paediatric heart transplant recipients. The second aim was to compare textural features of parametric maps in cases of rejection versus those without rejection.
Eligibility
Participation Requirements
Sex: All
Maximum Age: 18
Healthy Volunteers: f
View:
• children and young adults (transplanted when they were ≤ 18 years) who undergo an EMB for routine surveillance without contraindications to contrast-enhanced CMR
Locations
Other Locations
Italy
IRCCS Azienda Ospedaliero-Universitaria di Bologna
RECRUITING
Bologna
Contact Information
Primary
Valentina Gesuete, MD
valentina.gesuete@aosp.bo.it
0390512149096
Time Frame
Start Date: 2023-12-12
Estimated Completion Date: 2029-12-31
Participants
Target number of participants: 30
Related Therapeutic Areas
Sponsors
Leads: IRCCS Azienda Ospedaliero-Universitaria di Bologna