Hepatectomy Clinical Trials

Clinical trials related to Hepatectomy Procedure

Impact of Pringle Maneuver on the Occurrence of Postoperative Gallbladder Diseases After Hepatectomy: A Multicenter Retrospective Cohort Study

Status: Recruiting
Location: See all (8) locations...
Intervention Type: Procedure
Study Type: Observational
SUMMARY

The liver is an organ with a rich blood supply. During liver surgery (hepatectomy), surgeons often temporarily clamp the blood vessels supplying the liver to maintain a clear surgical field and reduce bleeding. This common technique is known as the Pringle maneuver. However, this maneuver also temporarily cuts off the blood supply to the gallbladder. Currently, doctors debate whether to routinely remove a healthy gallbladder during liver surgery to prevent future gallbladder problems, or to preserve it. The primary purpose of this multicenter retrospective cohort study is to evaluate whether using the Pringle maneuver during liver surgery increases the risk of patients developing gallbladder diseases (such as gallstones or inflammation) later on. Researchers will review the past medical records of patients who underwent liver surgery with their gallbladder preserved between January 2012 and January 2022. By comparing patients who had the Pringle maneuver with those who did not, the study aims to provide reliable clinical evidence to help surgeons make better decisions about whether to preserve or remove the gallbladder during liver surgery.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 85
Healthy Volunteers: f
View:

• Aged 18 to 85 years.

• Definitive diagnosis of hepatic solid lesions confirmed by imaging (such as CT, MRI, or ultrasound) and/or pathology.

• Underwent elective hepatectomy with gallbladder preservation.

• Preoperative liver function evaluated as Child-Pugh class A or B.

• Preoperative American Society of Anesthesiologists (ASA) physical status classification of I, II, or III.

Locations
Other Locations
China
Xinqiao Hospital of Army Medical Universit
RECRUITING
Chongqing
Sun Yat-sen University Cancer Center
RECRUITING
Guangzhou
Zhujiang Hospital of Southern Medical University
RECRUITING
Guangzhou
The First Affiliated Hospital of Harbin Medical University
RECRUITING
Harbin
The First Affiliated Hospital of University of Science and Technology of China
RECRUITING
Hefei
Nanjing Drum Tower Hospital
RECRUITING
Nanjing
Tianjin Medical University Cancer Institute and Hospital
RECRUITING
Tianjin
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
RECRUITING
Wuhan
Contact Information
Primary
Jiwei Huang
huangjiwei@wchscu.cn
+86 18980606725
Backup
Jun Ji
jijun0317@163.com
+86 18752433889
Time Frame
Start Date: 2026-03-01
Estimated Completion Date: 2026-08
Participants
Target number of participants: 2000
Treatments
Pringle Maneuver Group
Patients who underwent elective hepatectomy with gallbladder preservation and received Pringle maneuver during the surgery.
Non-Pringle Maneuver Group
Patients who underwent elective hepatectomy with gallbladder preservation but did not receive Pringle maneuver or any other specific vascular occlusion during the surgery.
Sponsors
Collaborators: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, Sun Yat-Sen University Cancer Center, The First Affiliated Hospital of University of Science and Technology of China, Southern Medical University, China, Tongji Hospital, First Affiliated Hospital of Harbin Medical University, Army Medical University, China, Tianjin Medical University Cancer Institute and Hospital
Leads: West China Hospital

This content was sourced from clinicaltrials.gov