Hip Replacement Clinical Trials

Clinical trials related to Hip Replacement Procedure

Comparison of Ultrasound-Guided QLESP Block Versus Pericapsular Nerve Group Block Combined With Lateral Femoral Cutaneous Nerve Block on Postoperative Analgesia and Functional Recovery in Total Hip Arthroplasty: A Randomized Controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Drug, Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Total hip arthroplasty (THA) is a common surgery to replace damaged hip joints, but many patients experience significant pain after surgery, which can delay recovery and increase the need for strong pain medications (opioids). Nerve blocks are a technique where anesthetic medication is injected near specific nerves to reduce pain. This study compares two different ultrasound-guided nerve block techniques for pain control after THA: the QLESP block (a newer technique that targets two areas with a single injection) and the PENG block combined with the LFCN block (a currently used technique that targets nerves around the hip joint and the outer thigh). Participants in this study will be randomly assigned (like a coin flip) to receive either the QLESP block or the PENG+LFCN block after surgery. The study aims to determine which nerve block provides better pain relief and reduces the need for opioid pain medications in the first 24 hours after surgery. Pain scores, recovery of leg movement, time to first walk, length of hospital stay, and any side effects will also be compared between the two groups.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: f
View:

• Age 18 to 70 years

• Scheduled for elective unilateral total hip arthroplasty via posterolateral approach

• American Society of Anesthesiologists (ASA) physical status I-III

• Body mass index (BMI) \< 35 kg/m²

• Ability to understand pain scoring and patient-controlled analgesia (PCA) use

• Willing and able to provide written informed consent

Locations
Other Locations
China
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
RECRUITING
Wuhan
Contact Information
Primary
Xi Wu
wu2018whuh@163.com
+8615871715431
Time Frame
Start Date: 2026-08-19
Estimated Completion Date: 2027-02-28
Participants
Target number of participants: 136
Treatments
Experimental: QLESP Group
Participants receive ultrasound-guided QLESP block with 30 mL of 0.375% ropivacaine (15 mL between the erector spinae and transverse process, and 15 mL between the quadratus lumborum and psoas major).
Active_comparator: PENG+LFCN Group
Participants receive ultrasound-guided PENG block with 20 mL of 0.375% ropivacaine combined with LFCN block with 10 mL of 0.375% ropivacaine.
Related Therapeutic Areas
Sponsors
Leads: Huazhong University of Science and Technology

This content was sourced from clinicaltrials.gov

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