Safety and Effectiveness Evaluations of the COLO-BT™ (Colorectal Balloon Tube) as an Alternative Treatment to the Temporary Ileostomy Following Proctectomy

Status: Recruiting
Location: See all (3) locations...
Intervention Type: Device, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of this study is to evaluate the Colorectal Balloon Tube (hereinafter referred to as COLO-BT™) device, a single use, temporary intraluminal bypass device, intended to reduce contact of fecal content with an anastomotic site, following colorectal surgery (open or laparoscopic)

Eligibility
Participation Requirements
Sex: All
Minimum Age: 19
Maximum Age: 80
Healthy Volunteers: t
View:

‣ The patient must meet all study Inclusion Criteria as outlined below:

• Adult males or females, 19-80 years of age, with signed informed consent

⁃ Subject whose anastomosis is expected to be located above 4cm from the anus, and at or below 15cm from the anus. (4cm \< inclusion target ≤ 15cm from the anus).

⁃ ③ Patient must meet all other inclusion criteria to be eligible. While not required, if one or more of the following six risk factors for postoperative anastomotic leakage\[6,7,8\] is true, the patient will be considered a high-risk subject:

⁃ \- Male

⁃ \- Those with a body mass index of 30 or higher

⁃ \- Current smoker

⁃ \- Those who are on medication for diabetes

⁃ \- Those with clinical stage III or higher malignant tumors

⁃ \- Those who received chemo/radiation therapy before surgery

⁃ ④ Those who are willing and able to participate in this clinical study, provide Informed Consent, and are willing to comply with the study procedures and follow up evaluations

⁃ ⑤ Those who have willingness to undertake blood transfusion if required.

Locations
United States
New York
Jacobs School of Medicine & Biomedical Sciences, State University of New York at Buffalo
RECRUITING
Buffalo
Pennsylvania
PennState Health - Milton S. Hershey Medical Center
RECRUITING
Hershey
Texas
Baylor College of Medicine
RECRUITING
Houston
Contact Information
Primary
Kim
jakehykim@jsrmed.co.kr
+82-10-9345-1058
Time Frame
Start Date: 2023-12-04
Estimated Completion Date: 2027-03-15
Participants
Target number of participants: 256
Treatments
Experimental: COLO BT™
Patients receive COLO BT™ during colorectal surgery.
Active_comparator: Standard of Care
Patients receive the standard of care, a protective stoma, during colorectal surgery.
Related Therapeutic Areas
Sponsors
Leads: JSR Medical Co., Ltd.

This content was sourced from clinicaltrials.gov