Comparison of the Effectiveness of Sciatic Nerve, Biceps Femoris Short Head (BiFeS) and Interspace Between the Popliteal Artery and the Capsule of the Posterior Knee (IPACK) Blocks Added to the Adductor Canal Block for Postoperative Pain Control in Patients Undergoing Primary Total Knee Arthroplasty: A Prospective, Randomized Controlled Clinical Trial

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Postoperative pain following total knee arthroplasty (TKA) is a significant clinical problem that delays early mobilization, reduces patient satisfaction, and increases analgesic requirements. The adductor canal block (ACB), which aims to provide analgesia while preserving motor function, is widely used in postoperative pain management after TKA. However, clinical and anatomical studies have demonstrated that ACB is effective only in the anteromedial sensory innervation of the knee and does not adequately block pain originating from the posterior knee capsule. This limitation reduces analgesic effectiveness, particularly in patients with a prominent posterior pain component. The sciatic nerve block has long been considered the gold standard for managing posterior knee pain. However, due to disadvantages such as motor weakness and delayed rehabilitation, current pain management protocols increasingly favor motor-sparing and complementary approaches such as the Biceps Femoris Short Head (BiFeS) block and the Interspace Between the Popliteal Artery and the Capsule of the posterior Knee (IPACK) block for posterior knee analgesia. In light of this information, the aim of our study is to guide clinical practice by comparing the postoperative analgesic efficacy, motor function outcomes, and patient satisfaction associated with sciatic nerve, BiFeS, and IPACK block techniques-each administered as a supplement to the adductor canal block-in patients undergoing total knee arthroplasty, with the ultimate goal of determining the optimal block combination for postoperative pain control.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:

• Patients classified as American Society of Anesthesiologists (ASA) physical status I-III

• Patients undergoing primary total knee arthroplasty

• Patients undergoing unilateral total knee arthroplasty

• Patients between 18 and 75 years of age

Locations
Other Locations
Turkey
Erzincan Binali Yıldırım Üniversitesi
RECRUITING
Erzincan
Contact Information
Primary
mustafa somunkıran, anesthesiology resident
msomunkran@gmail.com
+905536327870
Backup
fethi akyol, Assistant Professor
fethi24@windowslive.com
+905055422992
Time Frame
Start Date: 2025-11-01
Estimated Completion Date: 2026-11-01
Participants
Target number of participants: 102
Treatments
Experimental: Adductor Canal Block + Sciatic Nerve Block
Procedure: Mid-Adductor Canal Block Procedure: Sciatic Nerve Block
Experimental: Adductor Canal Block + BiFeS Block
Procedure: Mid-Adductor Canal Block Procedure: BiFeS Block
Experimental: Adductor Canal Block + IPACK Block
Procedure: Mid-Adductor Canal Block Procedure: IPACK Block
Related Therapeutic Areas
Sponsors
Leads: Erzincan University

This content was sourced from clinicaltrials.gov

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