FIRESTONES : Impact of Forced Diuresis on the Residual Fragment Rate After Flexible Ureteroscopy for Destruction of Kidney Stones With Laser: a Randomized Controlled Two-parallel Group Multicenter Trial With Blinding Evaluation
Status: Recruiting
Location: See all (9) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY
In view of the positive results of the numerous studies conducted on forced diuresis after extra-corporeal lithotripsy, the investigators chose to evaluate forced diuresis by injection of Furosemide associated with intravenous hydration, which has never before been the subject of a specific analysis.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:
• Patients ≥ 18 years old and \< 80 years old
• With the need to perform a flexible ureteroscopy with destruction of the kidney stones with laser
• Participants covered by or entitled to social security
• Written informed consent obtained from the participant
• Ability for participant to comply with the requirements of the study
Locations
Other Locations
France
CHU d'Angers
RECRUITING
Angers
Hospices Civils de Lyon
RECRUITING
Lyon
CHU de Nice
RECRUITING
Nice
CHU de Nîmes
RECRUITING
Nîmes
CHU de Rennes
RECRUITING
Rennes
CHU de Rouen
RECRUITING
Rouen
CHU de Toulouse
RECRUITING
Toulouse
Clinique La Croix du Sud
RECRUITING
Toulouse
CHRU de Tours
RECRUITING
Tours
Contact Information
Primary
Marie-Lou LETOUCHE, MD
marielou.letouche@gmail.com
+33247474665
Time Frame
Start Date: 2024-01-04
Estimated Completion Date: 2026-04-03
Participants
Target number of participants: 374
Treatments
Experimental: Furosemide
Injection of 40 mg of Furosemide during 10 minutes after the end of the flexible ureteroscopy for destruction of kidney stones with laser.
No_intervention: Usual care
Usual care, without injection of Furosemide.
Related Therapeutic Areas
Sponsors
Leads: University Hospital, Tours