Efficacy and Safety of Neorenal Forte as Adjuvant Treatment for the Complete Elimination of Residual Fragments After Flexible Ureterorenoscopy With Laser Lithotripsy for Renal Calculi.

Status: Recruiting
Location: See all (9) locations...
Intervention Type: Dietary supplement
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of this study is to evaluate the efficacy of a specialized formula of phytotherapeutic extracts (Neorenal Forte) aiding the complete elimination of residual fragments after fURS in adults.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
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• Male or female 18 to 65 years of age.

• The subject has signed informed consent approved by an Ethics Committee and agrees to the on-site study visits.

• A stone confirmed by NCCT of kidney, ureter and urinary bladder for assessment of size, number, location and stone density, within 90 days of fURS.

• Single or multiple kidney stones with total size of 10x10 mm to 15x10 mm.

• Stone density 1001 - 1400 Hounsfield units (HU).

• Subjects post fURS for laser lithotripsy of kidney stone.

• Residual fragments \< 4 mm after fURS confirmed by ultrasound on first postoperative day.

• Subjects post one fURS.

• fURS uncomplicated by perforation of ureter, mucosal exfoliation, damage to kidney or urinary bladder, serious bleeding or other complications.

⁃ No recent ureterorenoscopy within the last 6 months.

⁃ Body mass index 17.0 - 29.99 kg/m2 118

⁃ In Investigator's opinion, the subject can comply with the visit schedule and the treatment regimen and is capable of completing the study.

⁃ The subject has a smartphone and is capable of using it.

Locations
Other Locations
Bulgaria
MHAT Heart and Brain
RECRUITING
Burgas
UMHAT Dr. Georgi Stranski
RECRUITING
Pleven
University Hospital for Active Treatment Saint Marina
RECRUITING
Pleven
UMHAT Kaspela
RECRUITING
Plovdiv
UMHAT St. George
RECRUITING
Plovdiv
Military Medical Academy
RECRUITING
Sofia
UMBALSM N. I. Pirogov
RECRUITING
Sofia
UMHAT Alexandrovska
RECRUITING
Sofia
UMHAT Sofiamed
RECRUITING
Sofia
Contact Information
Primary
Margarita Futekova
m.futekova@neopharm.bg
+359 888 151 579
Backup
Stefan Tunev, PhD
s.tunev@neopharm.bg
+359 888 786 540
Time Frame
Start Date: 2025-04-01
Estimated Completion Date: 2026-05-30
Participants
Target number of participants: 120
Treatments
Experimental: Neorenal Forte
Up to Day 10 after the endourological procedure - 2 tablets 2 times daily Followed by 80 days after end date of 2X2 dose - 1 tablet 2 times daily
Placebo_comparator: Placebo
Up to Day 10 after the endourological procedure - 2 tablets 2 times daily Followed by 80 days after end date of 2X2 dose - 1 tablet 2 times daily
Related Therapeutic Areas
Sponsors
Leads: Neopharm Bulgaria Ltd.

This content was sourced from clinicaltrials.gov