A Single-Center Clinical Study on the Efficacy and Safety of Vortex Intelligence Stone Optimized Removal (VISOR)

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Goal of this trial: To test a new tool called VISOR in adults (aged 18-80) with 1-3 cm kidney or ureter stones. We want to see: 1. If it's safe and works well 2. If its built-in features (flushing/suction, pressure control, and stone-breaking/removal) help clear stones better while keeping surgery safe. Main questions: 1. Can the VISOR clear stones successfully (with fragments \<4 mm left) for at least 9 out of every 10 people within 24 hours after surgery? 2. Will serious problems (like severe infections or ureteral injuries) happen to no more than 1 in 20 people (5%)? 3. Can the device keep pressure inside the kidney below 30 mmHg (a safe level) during the entire surgery? What participants will do: Have stone removal surgery using VISOR (breaks and removes stones at the same time). Get a CT scan within 24 hours after surgery to check if stones are cleared. Return 4 weeks (±1 week) after surgery for: An imaging test (CT or ultrasound) A check for any health problems related to the surgery.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• Patients with upper urinary tract calculi, where the maximum diameter of a single calculus or the cumulative diameter of multiple calculi is 1-3 cm

• Patients who choose to undergo flexible ureteroscopic holmium laser lithotripsy

• Aged 18-80 years, regardless of gender

• Subjects without mental illness or language dysfunction, who can understand the details of this study and sign the informed consent form

Locations
Other Locations
China
2nd Affiliated Hospital, School of Medicine, Zhejiang University
RECRUITING
Hangzhou
Contact Information
Primary
Bohan Wang, MD., Ph.D
wangbohan@zju.edu.cn
+86-13575799866
Backup
Wenjun Gao, MD., Ph.D
gaowenjun@zju.edu.cn
+86-19817482099
Time Frame
Start Date: 2025-08-06
Estimated Completion Date: 2027-02-28
Participants
Target number of participants: 20
Treatments
Experimental: VISOR Treatment
All enrolled participants (n=20) will undergo upper urinary tract stone removal using the investigational device VISOR (Vortex Intelligence Stone Optimized Removal). The procedure includes:~1. Integrated irrigation-aspiration and real-time pressure monitoring/control (safety threshold: \<30 mmHg).~2. Holmium laser lithotripsy with simultaneous stone fragment removal.~3. Postoperative assessment:~Urinary CT scan at 24h to determine immediate stone-free rate (residual stones \<4 mm).~Follow-up imaging (CT/ultrasound) and complication monitoring at 28±7 days.
Related Therapeutic Areas
Sponsors
Leads: Second Affiliated Hospital, School of Medicine, Zhejiang University

This content was sourced from clinicaltrials.gov