Evaluation of the Patellar LIFT System for Subjects With Patellofemoral Cartilage Degeneration

Status: Recruiting
Location: See all (5) locations...
Intervention Type: Other, Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The PELICAN study is a prospective, non randomized, dual arm, multi-center clinical study comparing clinical outcomes of subjects treated with the LIFT Implant System to subjects treated with Tibial Tubercle Osteotomy (TTO).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 22
Maximum Age: 65
Healthy Volunteers: f
View:

• Patients age 22 to 65 years at time of screening

• Anterior knee pain due to patellofemoral cartilage degeneration (PCD) with an Modified Outerbridge score of ≥3 as assessed by an MRI on the study knee

• Body Mass Index (BMI) of ≤ 35

• Weight \< 300 lbs

• Anterior Knee Pain Score (AKPS) of ≤ 70 (0-100 scale)

• Visual Analog Score (VAS) of ≥ 40 (0-100 scale)

• Failure of at least 6 months of non-surgical treatment defined as at least one of the treatments (e.g. rest, bracing, physical therapy, targeted exercise, use of NSAIDs, activity level reduction or Confidential ZKR Orthopedics, CIP 0001 Page 11 of 55 Protocol Version: 1.0, 04JAN2024 modification, etc.) per AAOS Treatment of Osteoarthritis of the Knee; Evidence based guideline 3rd Edition 2021

Locations
United States
California
Horizon Clinical Research
RECRUITING
La Mesa
New York
Hospital for Special Surgery
RECRUITING
New York
NYU Langone Health
RECRUITING
New York
Ohio
Ohio State University - Jameson Crane Sports Medicine Institute
RECRUITING
Columbus
Oregon
Oregon Health and Science University
RECRUITING
Portland
Contact Information
Primary
Sharon Branch
clinadmin@zkrorthopedics.com
9543033777
Backup
Jeff Halbrecht, MD
jhalbrecht@zkrorthopedics.com
4152050496
Time Frame
Start Date: 2024-06-19
Estimated Completion Date: 2031-09
Participants
Target number of participants: 245
Treatments
Experimental: Treatment Group: LIFT
Subjects receiving the LIFT implant system.
Active_comparator: Control Group: TTO
Subjects receiving a Tibial Tubercle Osteotomy (TTO)
Related Therapeutic Areas
Sponsors
Leads: ZKR Orthopedics Inc

This content was sourced from clinicaltrials.gov