Long-term Clinical and Radiographic Outcomes of Different Knee Osteotomy Techniques for the Treatment of Compartmental Knee Osteoarthritis With Lower Limb Malalignment.

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

The present study aims to evaluate the long-term and medium-term outcomes of different knee osteotomy techniques in the treatment of knee osteoarthritis in patients with lower limb malalignment. This evaluation is necessary in the current context of research on the treatment and prevention of knee osteoarthritis through treatments that do not involve or allow for the postponement of prosthetic replacement. Among the biological treatments performed in orthopedic clinical practice, osteotomy is one of the most promising. However, further long-term evaluations are needed to more clearly determine the indications and potential of this type of intervention, considering the various surgical procedures described for performing it.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: f
View:

• Patients undergoing corrective knee osteotomy and any associated procedures such as meniscal repair/resection/replacement, ligament reconstruction, chondral treatment, or regenerative infiltrative treatment;

• Patients aged between 18 and 70 years at the time of surgical intervention;

• Patients with isolated compartmental osteoarthritis;

• Patients with a varus or valgus knee alignment defect of at least 3° compared to mechanical neutrality.

Locations
Other Locations
Italy
IRCCS Istituto Ortopedico Rizzoli
RECRUITING
Bologna
Contact Information
Primary
Stefano Zaffagnini
stefano.zaffagnini@ior.it
0516366075
Time Frame
Start Date: 2023-01-12
Estimated Completion Date: 2025-12-30
Participants
Target number of participants: 150
Treatments
Closing wedge
Patients undergoing closing wedge high tibial osteotomy in knee ostheoarthritis and lower limb malalignement
Opening wedge
Patients undergoing opening wedge high tibial osteotomy in knee ostheoarthritis and lower limb malalignement
Related Therapeutic Areas
Sponsors
Leads: Istituto Ortopedico Rizzoli

This content was sourced from clinicaltrials.gov