Effectiveness of Bromelain Supplement in Reduction of Facial Swelling Caused by Orthognathic Surgery

Status: Recruiting
Location: See location...
Intervention Type: Dietary supplement
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to learn if Bromelain Supplement works to decrease the amount of swelling or the amount of time swelling is present following jaw surgery. It will also learn about the safety of Bromelain supplement. The main questions it aims to answer are: Does Bromelain decrease facial swelling following orthognathic, or jaw, surgery? Does Bromelain supplement decrease the amount of time that patients are swollen following orthognathic, or jaw, surgery? Participants will: Take Bromelain supplement once daily for 9 days total. Take 2 days before surgery and 7 days following surgery. Keep a log of when the bromelain supplement is taken as well as another other medications. Visit the clinic with pre and post surgical protocol

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:

• undergoing orthognathic surgery

Locations
United States
Kentucky
University of Kentucky
RECRUITING
Lexington
Contact Information
Primary
Emma E Palmer, DMD
emma.palmer@uky.edu
859-358-6346
Time Frame
Start Date: 2025-09-08
Estimated Completion Date: 2026-04
Participants
Target number of participants: 200
Treatments
Experimental: Bromelain Supplement
1000mg bromelain supplement once a day, 2 days prior to and 7 days following surgery
No_intervention: Control
Standard of care
Related Therapeutic Areas
Sponsors
Leads: Mohamed Bazina

This content was sourced from clinicaltrials.gov