Other: Single Arm Intervention

1. Chemotherapy: 6 cycles (three months) of IV combination chemotherapy with mFOLFIRINOX on day 1 followed by one week of rest (14-day cycle). Alternatively, patients will receive three months of gemcitabine / nab-paclitaxel.~2. Re-staging CT scan with Carbohydrate Antigen (CA) 19-9 serum test.~3. Staging laparoscopy to rule out occult metastatic disease is optional based on surgeon's preference.~5\. Pancreatectomy 4 weeks following the last day of Chemotherapy as per standard of care.~6\. Adjuvant chemotherapy: as per standard of care. 7. Clinical assessment and CT scan with CA 19-9 serum test at 4-month intervals until identification of cancer recurrence.~8\. Follow up of patients after 2 years every six months for up to 5 years following the initiation of treatment will be performed off-protocol as per standard of care.