Algorithm-based Tailoring of Dual Antiplatelet Therapy to Improve Outcomes Following Percutaneous Coronary Interventions
Status: Recruiting
Location: See all (3) locations...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The use of aspirin combined with a P2Y12 inhibitor (dual antiplatelet therapy, DAPT) represents the standard of care for patients undergoing percutaneous coronary intervention (PCI) with stent implantation. The TAILOR-DAPT trial aims to investigate the benefits of a score-based decision-making algorithm to guide DAPT duration compared to a standard-of-care DAPT duration without the use of risk scores in patients undergoing PCI.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• PCI with drug eluting stent (DES) implantation
• Age ≥18 years
• Ability to sign informed consent before any study-specific procedure
Locations
Other Locations
Bosnia and Herzegovina
University Clinical Center of the Republic of Srpska
RECRUITING
Banja Luka
Italy
UOC Cardiologia San Giovanni Addolorata Hospital
RECRUITING
Roma
Switzerland
Department of Cardiology, Bern University Hospital
RECRUITING
Bern
Contact Information
Primary
Lorenz Räber, MD, PhD
Lorenz.raeber@insel.ch
+41 31 632 09 29
Backup
Miklos Rohla, MD, PhD
miklos.rohla@insel.ch
+41 31 632 21 11
Time Frame
Start Date: 2023-06-27
Estimated Completion Date: 2028-12
Participants
Target number of participants: 2788
Treatments
Experimental: Intervention
Algorithm-guided DAPT duration
Active_comparator: Standard
Standard-of-care DAPT duration
Related Therapeutic Areas
Sponsors
Leads: Insel Gruppe AG, University Hospital Bern