Percutaneous Coronary Intervention (PCI) Clinical Trials

Clinical trials related to Percutaneous Coronary Intervention (PCI) Procedure

Investigation of Clinical Characteristics, Frailty, and Predictors of In-Hospital and Six-Month Prognosis in Hospitalized Patients Aged 75 Years and Older With Acute Coronary Syndrome

Status: Recruiting
Location: See location...
Intervention Type: Other, Procedure
Study Type: Observational
SUMMARY

This study will evaluate clinical characteristics, frailty, and predictors of prognosis in patients aged 75 years and older who are hospitalized with acute coronary syndrome (ACS). The research includes both a retrospective and a prospective cohort. The aim is to determine whether frailty scores, combined with clinical and laboratory parameters available at admission, can improve risk prediction for complications and mortality compared with standard risk scores (TIMI, GRACE, Syntax). The study will also compare outcomes between patients treated with percutaneous coronary intervention (PCI) and those treated conservatively with medications. Patients will be followed during hospitalization and for six months after discharge. The results are expected to contribute to more personalized treatment strategies for elderly patients with ACS.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 75
Healthy Volunteers: f
View:

• Age ≥ 75 years

• Diagnosis of acute coronary syndrome (STEMI, NSTEMI, or unstable angina)

• Hospitalization in a tertiary care center (University Clinical Center Niš)

• For prospective cohort: signed informed consent

Locations
Other Locations
Serbia
Clinical Center Niš
RECRUITING
Niš
Contact Information
Primary
Svetlana Apostolović
drapostolovic@gmail.com
+381631094144
Time Frame
Start Date: 2026-05-13
Estimated Completion Date: 2027-09
Participants
Target number of participants: 550
Treatments
Hospitalized Patients ≥75 Years With Acute Coronary Syndrome
Patients aged 75 years and older admitted with acute coronary syndrome (STEMI, NSTEMI, or unstable angina). Data will be collected retrospectively and prospectively, including clinical, laboratory, echocardiographic, angiographic, and frailty parameters. Outcomes will be assessed during hospitalization and at 6 months after discharge.
Sponsors
Collaborators: University of Nis
Leads: Clinical Center Niš

This content was sourced from clinicaltrials.gov