Assessment of the Impact of Transcatheter Stenting of Aortic Coarctation on the Left Ventricular Afterload and Work Using Left Ventricular Pressure Volume Loops
Status: Recruiting
Location: See all (7) locations...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY
Coarctation of the aorta accounts for 4-7% of all congenital heart disease. While stent therapy, when feasible, is the standard of care for coarctation, it may not completely improve the work (and afterload) of the heart due to its effects on the elasticity of the aorta. This study will provide the information needed to understand the effects of current management on the cardiac mechanics and work.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 6
Healthy Volunteers: f
View:
• Children 6 years of age and older and adults of all races and both sexes referred for elective cardiac catheterization and stent therapy for coarctation
• Those who provide informed consent for study participant.
Locations
United States
California
Children's Hospital of Los Angeles
RECRUITING
Los Angeles
Massachusetts
Children's Hospital of Boston
RECRUITING
Boston
Michigan
Helen DeVos Children's Hospital
RECRUITING
Grand Rapids
Minnesota
University of Minnesota
RECRUITING
Minneapolis
Missouri
Children's Mercy Hospital
RECRUITING
Kansas City
Ohio
Cincinnati Children's Hospital
RECRUITING
Cincinnati
Texas
University of Texas-Southwestern
RECRUITING
Dallas
Contact Information
Primary
Brittany Faanes
grego318@umn.edu
612-625-5929
Time Frame
Start Date: 2019-06-04
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 20
Treatments
Pressure-volume loop catheter
Related Therapeutic Areas
Sponsors
Leads: University of Minnesota