The GORE VBX FORWARD Clinical Study: A Comparison of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis to Bare Metal Stenting for Patients With Complex Iliac Occlusive Disease

Status: Recruiting
Location: See all (7) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The objective of this prospective, multicenter, randomized, controlled clinical trial is to demonstrate the superiority of the VBX Device for primary patency when compared to bare metal stenting in complex iliac occlusive disease.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Age ≥ 18 years at time of informed consent signature

• Informed Consent Form (ICF) is signed by the subject

• Subject can comply with protocol requirements, including follow-up

• Patient has symptomatic claudication, rest pain, or minor tissue loss (Rutherford Category 2-5)

• Patient has de novo or restenotic lesion(s) found in the common and/or external iliac artery(ies)

• Patient has: Unilateral or bilateral single or multiple lesions (\>50% stenosis or chronic total occlusion) each between 4 and 11 cm in length

• Patient has a target vessel diameter visually estimated to be approximately between 5 mm and 13 mm

• Patient has a sufficient (\<50% stenotic) common femoral artery and at least one sufficient (\<50% stenotic) femoral artery (deep or superficial).

• Patient has at least one sufficient (\<50% stenotic) infrapopliteal run-off vessel.

Locations
United States
Colorado
North Suburban Medical Center
RECRUITING
Denver
Florida
Radiology and Imaging Specialists of Lakeland
RECRUITING
Lakeland
Pennsylvania
University of Pennsylvania
RECRUITING
Philadelphia
Texas
The University of Texas Southwestern Medical Center
NOT_YET_RECRUITING
Dallas
Other Locations
Germany
Krankenhaus der Barmherzigen Brüder
RECRUITING
Regensburg
Netherlands
Rijnstate Hospital
RECRUITING
Arnhem
New Zealand
Auckland City Hospital
RECRUITING
Auckland
Contact Information
Primary
Makensley Lordeus
mlordeus@wlgore.com
623-234-5989
Time Frame
Start Date: 2023-10-17
Estimated Completion Date: 2032-01-31
Participants
Target number of participants: 244
Treatments
Active_comparator: VBX Device Group
Subject in this group will receive treatment with the GORE VIABAHN® VBX Balloon Expandable Endoprosthesis (VBX)
Active_comparator: BMS Control Group
Subjects in this group will receive treatment with a commercially available bare metal stent (BMS) that is approved for treatment of the disease
Sponsors
Leads: W.L.Gore & Associates

This content was sourced from clinicaltrials.gov