Remote Ischemic Conditioning Plus Stenting for Symptomatic Carotid Artery Stenosis (RICSICAS): A Prospective, Randomized Controlled, Blind Endpoint, Single-Center Study
Remote ischemic conditioning (RIC) has emerged as a promising non-invasive strategy to protect the brain, with evidence suggesting its benefit in patients with carotid artery stenting (CAS). However, the long-term benefit and safety of chronic RIC in this population remain unknown. This trial aims to evaluate whether chronic RIC reduces the incidence of major vascular events and improves clinical outcomes in high-risk patients with carotid artery stenosis who received CAS.
• Age ≥ 40 years old;
• Patients with symptomatic moderate to severe stenosis of the internal carotid artery;
• History of ipsilateral cerebral ischemic symptoms within the past 180 days;
• Planned for carotid artery stent;
• Essen Score ≥ 3;
• Modified Rankin Scale score of 0 or 1;
• Signed informed consent.