Feasibility and Efficacy of Intra- Arterial TNK and Albumin as an Adjunct to Thrombectomy for Acute Stroke
Status: Recruiting
Location: See location...
Intervention Type: Drug, Other
Study Type: Interventional
Study Phase: Phase 3
SUMMARY
The purpose of this study is to investigate the feasibility and efficacy of intra-arterial TNK and albumin for patients with acute ischemic stroke after successful thrombectomy and whether there is a synergistic effect between TNK and albumin.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:
• AIS patients with large vessel occlusion;
• Age between 18 and 80 years;
• Baseline NIHSS score ≥ 6; 4 .Successful recanalization after thrombectomy (mTICI grades ≥ 2b);
⁃ 5\. ASPECTS score ≥ 6 on CT; 6. First episode or previous episode without significant sequelae (mRS ≤ 2); 7. Time from onset to femoral artery puncture ≤ 24 hours; 8. Written informed consent provided by the patients or their legal relatives.
Locations
Other Locations
China
Tianjin Huanhu Hospital
RECRUITING
Tianjin
Time Frame
Start Date: 2023-09-07
Estimated Completion Date: 2024-09-07
Participants
Target number of participants: 80
Treatments
Active_comparator: Intra-Arterial TNK and Albumin
Active_comparator: Intra-Arterial TNK
Active_comparator: Intra-Arterial Albumin
Sham_comparator: sham
Related Therapeutic Areas
Sponsors
Leads: Tianjin Huanhu Hospital