FORWARD: Functional Outcomes in Real-World Treatment And Revascularization of Non-dominant and Distal M2 Occlusions
The objective of this study is to collect safety and effectiveness data on the Penumbra System reperfusion catheters in participants with isolated primary non-dominant and distal M2 occlusions who undergo endovascular mechanical thrombectomy (EVT). Additionally, this study aims to observe characteristics and outcomes of participants treated with medical management (MM) alone and those who receive EVT + MM per current medical practice.
• Participant age ≥ 18
• Participant experiencing acute ischemic stroke due to a confirmed primary M2 occlusion in the vertical segment or post-bifurcation in the non-dominant or co-dominant branch of the horizontal segment
• NIHSS ≥5 or NIHSS 3-4 with disabling symptoms
• Pre-stroke mRS 0-1
• For participants undergoing thrombectomy: Planned first-line treatment with Penumbra System reperfusion catheters
• Informed consent obtained per Institutional Review Board/Ethics Committee requirements