Contribution of Indocyanine Green Angiography in the Detection of Parathyroids and the Prevention of Hypoparathyroidism Post Total Thyroidectomy

Who is this study for? Adults having to undergo a total thyroidectomy
What treatments are being studied? Indocyanine green
Status: Recruiting
Location: See location...
Intervention Type: Drug, Procedure
Study Type: Interventional
Study Phase: Phase 3
SUMMARY

* Hypoparathyroidism is the most common complication after a total thyroidectomy surgery. It becomes permanent after 6 months. * Untreated permanent hypoparathyroidism is a source of numerous complications in general and therefore requires lifelong replacement therapy resulting in a significant deterioration in quality of life. * The intraoperative use of indocyanine green (ICG) angiography has recently been described as a reliable means of detecting parathyroidism and predicting the risk of postoperative hypoparathyroidism. * This use could prove to be a way to preserve parathyroid in vivo and thus reduce post-operative hypoparathyroidism rates.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Patient having to undergo a total thyroidectomy

• Signed consent

• Patient beneficiary of a social security regimen

Locations
Other Locations
France
CHRU de Brest
RECRUITING
Brest
Contact Information
Primary
Jean-Christophe LECLERE, PhD
jean-christophe.leclere@chu-brest.fr
0298223630
Time Frame
Start Date: 2021-06-22
Estimated Completion Date: 2025-03
Participants
Target number of participants: 242
Treatments
Experimental: ICG group
Patient receiving 2 or 3 intraoperative injections of indocyanine green.
Other: Control group
Patient benefiting from the traditional surgical act
Related Therapeutic Areas
Sponsors
Leads: University Hospital, Brest

This content was sourced from clinicaltrials.gov