A Pilot Investigation to Determine the Utility of Liquid Biopsies and Tumor Molecular Profiling in Predicting Recurrence in Endometrial Cancer
Status: Recruiting
Location: See location...
Intervention Type: Procedure, Other
Study Type: Observational
SUMMARY
This study is to find out how well liquid biopsies work as a non-invasive alternative to other methods of finding cancer cells (such as a tissue biopsy) in patients with endometrial cancer. A liquid biopsy is a blood test that may be able to find cancer cells. Collecting and storing samples of blood and tissue from patients with endometrial cancer to study in the laboratory may help doctors learn how the cells in the blood may change during treatment for uterine cancer.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Healthy Volunteers: f
View:
• Women age 18 years and older
• Histologic diagnosis of endometrial cancer
• Candidate for primary surgical treatment or has recently had prior primary surgery
• Willing and able to provide informed consent
Locations
United States
Texas
M D Anderson Cancer Center
RECRUITING
Houston
Contact Information
Primary
Pamela T Soliman, MD
psoliman@mdanderson.org
713-745-2352
Time Frame
Start Date: 2019-06-18
Estimated Completion Date: 2028-06-30
Participants
Target number of participants: 1000
Treatments
Observational (biospecimen collection, Pap smear)
Patients undergo collection of blood samples for liquid biopsy during pre-treatment consultation before hysterectomy, after hysterectomy but before starting any chemotherapy, and at the end of last chemotherapy cycle. Patients also undergo collection of tissue samples during hysterectomy. Patients may also undergo Pap smears before and after hysterectomy.
Related Therapeutic Areas
Sponsors
Leads: M.D. Anderson Cancer Center