Efficacy of Direct Selective Laser Trabeculoplasty (DSLT) for Reducing Medication Burden in Medically Controlled Patients With Ocular Hypertension or Primary Open Angle Glaucoma

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Observational
SUMMARY

This is a prospective, single arm, open label study conducted at a single site to evaluate the efficacy of Direct Selective Laser Trabeculoplasty (DSLT) in reducing medication burden in patients with medically controlled ocular hypertension or primary open angle glaucoma. The study will assess the primary endpoint of reduction in medication count at 6 months compared to baseline. Secondary endpoints include IOP reduction compared to baseline (both percentage and absolute), complete success rate (no increase in IOP without medications), proportion of eyes needing medication at 6 months, and any secondary surgical interventions at 6 months post-DSLT. Participants will undergo DSLT with 120 shots, 400 µm spot size, and 1.8mJ fixed energy delivered at the limbus over 2.4 seconds. Follow-up visits will occur at 1 month, 3 months, and 6 months post-procedure, with IOP measured using a calibrated Goldmann tonometer.

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:

• Adult patients scheduled to undergo DSLT treatment in one or both eyes.

⁃ Diagnosis of ocular hypertension or primary open angle glaucoma (POAG).

• Medically controlled on 1-3 topical ocular hypotensive agents with IOP ≤21 mmHg.

Locations
United States
Florida
The Eye Institute of West Florida
RECRUITING
Largo
Contact Information
Primary
Renee Bondurant
Renee.Bondurant@eyespecialist.com
727-450-4668
Time Frame
Start Date: 2026-02-26
Estimated Completion Date: 2027-01-26
Participants
Target number of participants: 60
Sponsors
Leads: The Eye Institute of West Florida
Collaborators: Sengi

This content was sourced from clinicaltrials.gov