Changes of Ascending Aortic Diameter in Patients Undergoing Transcatheter Aortic Valve Replacement

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Observational
SUMMARY

The goal of this observational study is to assess the changes of ascending aortic diameter in patients undergoing transcatheter aortic valve replacement. The main questions it aims to answer are: 1. whether the ascending aortic diameter increases or remains stable after transcatheter aortic valve replacement, especially in patients with preoperative ascending aortic dilatation; 2. the determinants of postoperative ascending aortic dilatation.

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:

• Severe aortic stenosis defined as an aortic valve area of 1cm2 or less or an indexed aortic valve area of 0.6cm2/m2 or less;

• Presence of clinical symptoms defined as a New York Heart Association functional class of 2 or more;

• High risk of surgical aortic valve replacement;

• Suitability for a transfemoral vascular access.

Locations
Other Locations
China
National Center for Cardiovascular Disease, China & Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
RECRUITING
Beijing
Contact Information
Primary
Xiangbin Pan, Dr
panxiangbin@fuwaihospital.org
0086-010-88396666
Backup
Kang An, Dr
ankang913@126.com
0086-15801301740
Time Frame
Start Date: 2022-03-22
Estimated Completion Date: 2025-03-21
Participants
Target number of participants: 480
Treatments
Transfemoral TAVR for AS
Patients undergoing transfemoral transcatheter aortic valve replacement for aortic stenosis
Sponsors
Leads: China National Center for Cardiovascular Diseases

This content was sourced from clinicaltrials.gov