Transcatheter Aortic Valve Implantation (TAVR): The Impact of Prothesis Positioning on Valvular and Coronary Hemodynamics

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The aim of this clinical study is to learn more about the effects of TAVR-prosthesis positioning on hemodynamics and the coronary arteries. The main questions it aims to answer are: 1. Does the cardiac magnetic resonance imaging and the echocardiography imaging provide an equivalent alternative to the computer tomography which is the state of the art in evaluating commissural alignment? 2. What effect does the position of the valve on the annular level have, especially its symmetrical and commissural position, on valvular and aortic blood flow characteristics? 3. What is the influence of symmetrical position and the presence of a commissural alignment on the coronary flow after transcatheter aortic valve replacement?

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:

• \- Patients who have undergone transfemoral transcatheter aortic valve replacement (TAVR).

Locations
Other Locations
Germany
Division of Cardiology, Pulmonary Disease and Vascular Medicine at University Hospital Duesseldorf
RECRUITING
Düsseldorf
Contact Information
Primary
Tobias Zeus, Prof
zeus@med.uni-duesseldorf.de
0211 81 18800
Backup
Kathrin Klein, Dr. med.
kathrin.klein@med-uni-duesseldorf.de
0211 81 08252
Time Frame
Start Date: 2024-10-22
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 100
Treatments
Other: TTE, TEE and MRI after TAVR
Each study patient will undergo transthoracic echocardiography, transesophageal echocardiography, and cardiac magnetic resonance imaging following transcatheter aortic valve replacement.
Sponsors
Leads: Heinrich-Heine University, Duesseldorf

This content was sourced from clinicaltrials.gov