Transcatheter Aortic Valve Replacement (TAVR) Clinical Trials

Clinical trials related to Transcatheter Aortic Valve Replacement (TAVR) Procedure

Association Between Changes in Aortic Valve Area and Pulmonary Congestion in Patients Undergoing Transcatheter Aortic Valve Implantation

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Observational
SUMMARY

This prospective, single-center observational study aims to evaluate the relationship between changes in aortic valve hemodynamics and pulmonary congestion in patients undergoing elective transfemoral transcatheter aortic valve implantation (TAVI) for severe symptomatic aortic stenosis. Pulmonary congestion will be assessed non-invasively using lung ultrasound, with particular emphasis on B-lines, at predefined time points before and after TAVI. Changes in aortic valve area and other echocardiographic parameters will be evaluated in relation to changes in lung ultrasound findings. The primary objective is to determine the association between improvement in aortic valve area following TAVI and changes in pulmonary congestion.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Age ≥18 years

• Diagnosis of severe symptomatic aortic stenosis

• Scheduled for elective transfemoral transcatheter aortic valve implantation (TAVI)

• Availability of preprocedural transthoracic echocardiography

• Feasibility of lung ultrasound examination

• Provision of written informed consent

Locations
Other Locations
Turkey
Istanbul University-Cerrahpasa, Cerrahpasa Faculty of Medicine
RECRUITING
Istanbul
Contact Information
Primary
Metin İlteray Kıkılı, MD
metin.kikili@iuc.edu.tr
+905439782131
Time Frame
Start Date: 2026-03-31
Estimated Completion Date: 2027-04
Participants
Target number of participants: 52
Treatments
TAVI Cohort
Patients with severe symptomatic aortic stenosis undergoing elective transfemoral transcatheter aortic valve implantation (TAVI) as part of routine clinical care. Lung ultrasound and echocardiographic assessments will be performed at predefined time points to evaluate changes in pulmonary congestion and aortic valve hemodynamics.
Sponsors
Leads: Istanbul University - Cerrahpasa

This content was sourced from clinicaltrials.gov