Efficacy of Intra-ureteric Aminophylline Instillation on Flexible Ureteroscopy Procedure: A Randomized Controlled Study
Status: Recruiting
Location: See location...
Intervention Type: Other, Drug, Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
in this study we are going to evaluate the efficacy of intra-ureteric aminophylline instillation in facilitating ureteric access sheath placement prior to flexible ureteroscopy in reducing ureteric injury rates.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:
• Upper ureteric stones or renal stones \< 2 cm
Locations
Other Locations
Egypt
Ain Shams University Hospitals
RECRUITING
Cairo
Contact Information
Primary
Ali Khaled Mohammed Ali Dr. Ali Khaled, MSc.
ali.khaled94@gmail.com
+201099978174
Backup
Younan Samir, PhD
dr_yona@live.com
+201201255511
Time Frame
Start Date: 2025-03-01
Estimated Completion Date: 2026-02-01
Participants
Target number of participants: 129
Treatments
Experimental: Group A: Aminophylline Group: Intra-ureteric instillation of aminophylline
a ureteric catheter 6 Fr will be used for instillation of normal saline supplemented with aminophylline 250 mg/10 mL at three points (Pelvi-ureteric junction, upper sacroiliac joint level and proximal to uretero-vesical junction by 5 cm) then wait for 5 minutes
Active_comparator: Group B: Ureteral Dilator Group: Traditional ureteral dilators
traditional ureteral dilators will be used. We will start by ureteral dilator 6 fr and gradually increase the size up to 12 Fr
Other: Group C: Combination Group: Aminophylline instillation and Ureteral dilators
Aminophylline will be instilled as in group (A) then followed by traditional ureteral dilatation as in group (B)
Related Therapeutic Areas
Sponsors
Leads: Ain Shams University