Autologous Semitendinosus Tendon Graft as Meniscal Transplant - a Clinical Pilot Study

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Observational
SUMMARY

Removal of meniscal tissue is described to result in poor knee function and a significant risk for future development of osteoarthritis. Different implants have been suggested to substitute a removed meniscus. Meniscal allograft transplantation is not widely available due to costs and availability. The semitendinosus tendon is a known graft with biological properties with potential to remodel and revascularize in an intraarticular environment such as anterior cruciate ligament reconstruction. The objective for this study was to investigate whether the semitendinosus tendon graft could function as a meniscal transplant.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 20
Maximum Age: 50
Healthy Volunteers: f
View:

• Previous subtotal or total meniscectomy

• Post meniscectomy symptoms

• No osteoarthritic changes on radiography more than Ahlbäck 1

• Knee aligment (hip-knee-angle) +/- 3°

• No persisting ACL insufficiency

Locations
Other Locations
Sweden
KISÖS
RECRUITING
Stockholm
Contact Information
Primary
Karl Eriksson, Prof
karl.eriksson@ki.se
0046707202646
Backup
Erik Rönnblad, MD
erik.ronnblad@ki.se
0046736785549
Time Frame
Start Date: 2018-01-01
Estimated Completion Date: 2026-01-01
Participants
Target number of participants: 10
Related Therapeutic Areas
Sponsors
Leads: Karolinska Institutet

This content was sourced from clinicaltrials.gov