Developing and Testing an Opioid Taper Intervention Before Total Knee Arthroplasty: Phase 2 Intervention Development

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to develop an pharmacist-led preoperative opioid taper intervention for patients undergoing total knee or hip replacement who are on chronic opioids before their surgery. The main questions it aims to answer are: * Is the intervention feasible and acceptable to patients? * Does the intervention result in a decrease in opioid dose during the preoperative period? Participants will meet with a clinical pharmacist, who will provide some basic education on pain and opioids, and will propose an opioid taper schedule. The pharmacist will then follow-up with the participant by phone each week until surgery to assess progress and adjust the taper as necessary.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• decided to pursue primary, unilateral total knee or hip arthroplasty with planned surgery date in 4-8 weeks

• currently taking between 20 and 90 MME of oral opioids, and that dose has been stable for at least 3 months

• have a reliable telephone number for contact

• speaks English

Locations
United States
Alabama
UAB Hospital-Highlands
RECRUITING
Birmingham
Contact Information
Primary
Kevin R Riggs, MD
kriggs@uabmc.edu
205-934-0778
Backup
Shakristal Williams
shakristalwilliams@uabmc.edu
205-934-2304
Time Frame
Start Date: 2024-01-10
Estimated Completion Date: 2026-09-01
Participants
Target number of participants: 45
Treatments
Experimental: Pharmacist-led opioid taper intervention
The participant will attempt to taper their opioid dose by \~50% during the 4-6 week preoperative period. Participants will meet with a clinical pharmacist, who will provide some basic education on pain and opioids, and will propose an opioid taper schedule. The pharmacist will then follow-up with the participant by phone each week until surgery to assess progress and adjust the taper as necessary.
Related Therapeutic Areas
Sponsors
Leads: University of Alabama at Birmingham
Collaborators: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

This content was sourced from clinicaltrials.gov