Mechanically or Kinematically Aligned Total Knee Prosthesis: Prospective and Comparative Study of Clinical, Stereoradiographic, and Biomechanical Results

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The mechanical alignment technique (Mechanical Alignment - MA) of a total knee prosthesis (TKA) was developed with the aim of making the installation of a TKA simple and reproducible, and that the prosthetic biomechanics are acceptable, thus promoting good longevity of implants. This is a technique that does not aim to restore the constitutional anatomy of the knee; bone cuts are systematically made at fixed angles, in the 3 planes of space, in relation to the mechanical axes of the long bones (femur and tibia). This non-personalized implantation technique therefore systematically alters the anatomy, laxity and kinematics of the knee, causing up to 50% of residual symptoms after prosthetic implantation and 20% of dissatisfied patients. In order to improve the clinical results of TKA, a new, more personalized and physiological technique was developed in 2007, called Kinematic Alignment (KA). This technique aims to restore the pre-arthritic anatomy, unique to each knee. Patients with severe constitutional deformity of the lower limb therefore retain this deformity after kinematic prosthetic replacement. The impact of the alignment technique on the biomechanics of the prosthetic knee remains poorly described. The main objective of this study is therefore to compare knee biomechanics between mechanical TKA and kinematic TKA.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Patient followed as part of a consultation 1 year after TKA placement

• Adult patient

• Patient affiliated to a social security system

• Patient informed of the study and formally included (signing of informed consent) before the first research review

Locations
Other Locations
France
Clinique du Sport Bordeaux Merignac
RECRUITING
Mérignac
Contact Information
Primary
Charles Rivière, MD
charles.riviere@bari-arthroplasty.com
+33 5 56 46 10 40
Time Frame
Start Date: 2023-10-05
Estimated Completion Date: 2025-09-30
Participants
Target number of participants: 120
Treatments
Experimental: patients with kinematic aligned knee prosthesis
Active_comparator: patients with biomechanic aligned knee prosthesis
Related Therapeutic Areas
Sponsors
Leads: Clinique du Sport, Bordeaux Mérignac

This content was sourced from clinicaltrials.gov