Distribution of Coronal Plane Alignment of the Knee Classification in Chinese Osteoarthritic as Well as Healthy Population

Status: Recruiting
Location: See location...
Intervention Type: Radiation
Study Type: Observational
SUMMARY

coronal plane alignment of the knee(CPAK) distribution of 246 cases(477 knees) of OA patients and 107 cases(214 knees) of healthy people were examined on long-leg radiographs retrospectively. Radiological measurements and CPAK classification on different Kellgren- Lawrence(K-L) Grade in patients with unilateral total knee arthroplasty(TKA) were compared. Clinical outcomes of CPAK type I patients performed by mechanical alignment(MA) and restricted kinematic alignment(rKA) during TKA were examined. ML algorithm including K nearest neighbors (KNN), random forest(RF), artificial neural networks (ANN), logistic regression(LR) and gradient boosting (GBDT) were established, the dependent variable was set as whether the constitutional phenotype of an arthritic knee classified as type I was type I.

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:

• \- OA group: Data for consecutive OA patients with knee pain who underwent primary TKA by one senior surgeon between August 2021 and July 2023 at a single institution were analyzed retrospectively.

• Healthy group: Data for consecutive visitors at outpatient clinic who underwent long-leg radiographs but without any sign of cartilage degeneration or medical history of low extremity between January 2023 and July 2023 at the same institution were analyzed retrospectively.

Locations
Other Locations
China
The First Hospital of Jilin University
RECRUITING
Changchun
Contact Information
Primary
Xin Qi, Dr.
dr.qixin@jlu.edu.cn
+8615843073202
Time Frame
Start Date: 2023-11-22
Estimated Completion Date: 2023-12-06
Participants
Target number of participants: 353
Treatments
OA group
Data for consecutive OA patients with knee pain who underwent primary TKA by one senior surgeon between August 2021 and July 2023 at a single institution were analyzed retrospectively. A total of 273 patients underwent long-leg radiographs. The following 27 patients were excluded from this study: prior total hip arthroplasty, 2; obvious bony deficiency of the femur or tibia, 10; simultaneous flexion of the knee and rotation of the leg on radiographs, 15. CPAK distribution of the remaining 246 cases(unilateral, 15; bilateral, 231; totally 477 knees) was examined.
healthy group
Data for consecutive visitors at outpatient clinic who underwent long-leg radiographs but without any sign of cartilage degeneration or medical history of low extremity between January 2023 and July 2023 at the same institution were analyzed retrospectively. A total of 136 visitors were recruited. The following 18 visitors were excluded from this study: extra-articular deformity of the femur or tibia, 15; simultaneous flexion of the knee and rotation of the leg on radiographs, 13; poor quality image, 1. CPAK distribution of the remaining 107 cases(214 knees) was examined.
Related Therapeutic Areas
Sponsors
Leads: The First Hospital of Jilin University

This content was sourced from clinicaltrials.gov