Auditory Stimulation Effect on Spindles and Sleep Dependent Learning in Rolandic Epilepsy
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The investigators are recruiting children with Rolandic epilepsy and children without epilepsy (aged 4 years old and above) for a non-invasive brain imaging study using Magnetic Resonance Imaging (MRI), Magnetoencephalography/Electroencephalography (MEG/EEG), and experimental tasks. The investigators hope to determine the brain circuits and brain rhythms affected in these children and ultimately identify new treatment options for childhood epilepsy patients.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 4
Maximum Age: 18
Healthy Volunteers: t
View:
• Ages 4-18 years
• Diagnosed with childhood epilepsy with centrotemporal spikes (CECTS) or Rolandic epilepsy by child neurologist
• Has EEG with sleep activated centrotemporal spikes
• Has had at least 1 focal motor or generalized seizure
Locations
United States
Massachusetts
Athinoula A. Martinos Center Biomedical Imaging
RECRUITING
Charlestown
Contact Information
Primary
Catherine Chu, MD
cjchu@mgh.harvard.edu
617-726-6540
Backup
Erin Berja, BS
eberja@mgh.harvard.edu
631-317-0413
Time Frame
Start Date: 2021-01-16
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 100
Treatments
Experimental: Children and adolescents with epilepsy and controls
Closed loop auditory stimulation during nap
Related Therapeutic Areas
Sponsors
Leads: Massachusetts General Hospital
Collaborators: Boston University, National Institute of Neurological Disorders and Stroke (NINDS)