Investigating the Effect of Closed-loop Auditory Stimulation on Sleep and Behavior in Patients With Epilepsy and Healthy Controls: a Developmental Study
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Objective: Characterizing the effects of down-phase-targeted auditory stimulation on behavior and sleep EEG characteristics and determine whether the changes in sleep EEG characteristics are associated with the changes in behavior and wake EEG characteristics.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 4
Maximum Age: 30
Healthy Volunteers: t
View:
• Participants of any gender
• Children, adolescents and young adults (4-30 years old)
• Right-handed
• Written informed consent by the participant or, if applicable, by their legal guardian after receiving information about the study For healthy participants:
• Good general health status
⁃ For patients with epilepsy:
• Diagnosed with epilepsy
• Wake or sleep EEG within the last 12 months showing epileptic discharges.
• Attending a regular school.
Locations
Other Locations
Switzerland
University Children's Hospital Zurich
RECRUITING
Zurich
Contact Information
Primary
Sven Leach, M. Sc.
sven.leach@kispi.uzh.ch
+41 44 266 3217
Time Frame
Start Date: 2020-07-29
Estimated Completion Date: 2025-12
Participants
Target number of participants: 120
Treatments
Experimental: Children (4-11y) with epilepsy
Down-phase-targeted closed-loop auditory stimulation is administered in each arm.
Experimental: Teenagers (12-17y) with epilepsy
Experimental: Young adults (18-30y) with epilepsy
Experimental: Healthy children (4-11y)
Experimental: Healthy teenagers (12-17y)
Experimental: Healthy young adults (18-30y)
Related Therapeutic Areas
Sponsors
Collaborators: ETH Zurich, University of Zurich
Leads: University Children's Hospital, Zurich