Brain Representation of Acquisition in Humans of Motor-Sensory Skills

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

Interactions between the perceptual and motor systems are fundamental to the performance of complex motor tasks and are at the heart of the fine motor control required for the production of complex sounds such as speech production or playing a musical instrument. In such situations, the brain must learn to generate relevant motor commands to a sound-producing system with fixed physical characteristics, such as the vocal tract or a musical instrument. No study has yet been able to directly test the dynamic aspect of this sensorimotor learning in an acoustic production task with fine motor control. The Adolphe de Rothschild Foundation Hospital takes care of patients requiring awake surgery. During these procedures, a direct cortical recording, called electro-corticography, is performed in order to better delineate the tumor or epileptogenic resection area. Reference recordings are made in healthy areas at a distance from the lesion site making it possible to record normal brain activity. In this case, we would propose to the patient to use a tool similar to the theremin (a musical instrument the size of a golf ball whose displacement in space modulates the frequency and the harmonics of a sound). The patient should therefore learn in order to create relevant motor patterns.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Benefiting from an intracranial brain recording during a programmed surgery in awake condition.

Locations
Other Locations
France
Fondation Adolphe de Rothschild
RECRUITING
Paris
Contact Information
Primary
Pierre Bourdillon, MD PHD
pbourdillon@for.paris
+33 1 48 03 66 12
Time Frame
Start Date: 2023-01-04
Estimated Completion Date: 2028-03
Participants
Target number of participants: 50
Related Therapeutic Areas
Sponsors
Leads: Fondation Ophtalmologique Adolphe de Rothschild

This content was sourced from clinicaltrials.gov