Vagus Nerve Stimulation for Autonomic Dysregulation in Individuals With Developmental Disorders
The goal of this flexible single-subject design vagus nerve stimulation (VNS) study is to examine the behavioral, cognitive, and biorhythmic effects of VNS in children and adults with autism and developmental disabilities. The main aims are: * Pilot the creation of a profile for those who will respond to VNS with the long-term goal of designing clinical trials. * Examine the effects of VNS on a broad range of symptoms. Participants will select between 1, 2, or 3 months of daily VNS treatment and complete study visits each month.
• Children and adults aged 12-40 with intellectual and developmental disability (IDD) and/or autism spectrum disorder (ASD). Participants who are decisionally-impaired will be eligible with assent.
• Able to tolerate wearing an Apple Watch, EEG, and sit for a neurocognitive test
• Be on a stable dose of psychotropic medication for at least one month prior to enrollment
• Agree not to initiate new or change existing medications or behavior intervention