Three-dimensional MR Elastography for Assessing Cirrhosis and Portal Hypertension (CHESS2206): a Prospective Multicenter Study
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Observational
SUMMARY
How to construct a novel, non-invasive, accurate, and convenient method to achieve prediction of hepatic venous pressure gradient (HVPG) is an important general problem in the management of portal hypertension in cirrhosis or advanced chronic liver disease. We plan to investigate the ability of three demensional-magnetic resonance elastography (3D-MRE) to establish a risk stratification system and perform tailored management for portal hypertension in cirrhosis or advanced chronic liver disease.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:
• age \> 18 years old
• confirmed cirrhosis or ACLD (advanced chronic liver disease) (laboratory, imaging and clinical symptoms)
• with 3D-MRE within 1 month prior to HVPG measurement
• written informed consent
Locations
Other Locations
China
Shengjing Hospital
RECRUITING
Shenyang
Contact Information
Primary
Yifei Huang, M.D.
huangyf1995@foxmail.com
+86 158 0000 4518
Backup
Yu Shi, Prof.
18940259980@163.com
+86 189 4025 9980
Time Frame
Start Date: 2022-08-16
Estimated Completion Date: 2025-12-01
Participants
Target number of participants: 100
Treatments
Training cohort
Training cohort was set to develop the novel non-invasive model for virtual HVPG
Validation cohort
Validation cohort was set to validate the novel non-invasive model for virtual HVPG in different people in same environments
Related Therapeutic Areas
Sponsors
Collaborators: Zhongda Hospital
Leads: Shengjing Hospital