Air Pollution and Cardiovascular Disease in Qatar: an Interventional Study to Reduce Blood Pressure: the APCIQ-BP Trial
The main objective is to determine if in-home portable air cleaners provide persistent reductions in PM2.5 exposures and improvements in systolic blood pressure and biochemical parameters over 4-weeks in patients with metabolic syndrome residing in Qatar.
• Non-smokers (100% abstinence from use of any smoking or vaping product during the prior year)
• Age ≥18 and less than 60 years old
• Living in a single residence (home, apartment) located anywhere in Qatar
• Mild systolic hypertension: screening visit systolic BP 130 to 159 mm Hg (off treatment or taking ≤ 2 BP medications that have been stable without changes during prior 4 weeks) plus ≥ 2 more additional criteria for the metabolic syndrome:
‣ Waist circumference ≥102 cm if male and ≥88 cm if female
⁃ Fasting triglycerides ≥150 mg/dL (or taking a triglyceride-lowering medication)
⁃ HDL-C ≤ 40 mg/dL if male and ≤ 50 mg/dL if female (or taking an HDL-raising medication),
⁃ Fasting glucose ≥100 mg/dL