Effect of High-intensity Interval Training Combined With DASH Diet on Arterial Stiffness in Hypertensive Patients: a Randomized Controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Procedure, Dietary supplement
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Cardiovascular disease (CVD) is one of the leading causes of mortality worldwide and a major risk factor for morbidity worldwide . It is necessary to reduce the incidence and risk factors of CVD, as physical activity is known to reduce mortality from CVD. Arterial stiffness and hypertension are closely related in pathophysiology. Chronic high blood pressure (BP) can lead to arterial wall damage by mechanical stress, endothelial dysfunction, increased inflammation, oxidative stress, and renin-angiotensin-aldosterone system (RAAS) activation. HIIT has been shown to be equally or even better at stimulating health benefits than moderate-intensity continuous training (MICT) and is considered a time-saving aerobic exercise for reducing arterial stiffness in HTN patients

Eligibility
Participation Requirements
Sex: All
Minimum Age: 35
Maximum Age: 50
Healthy Volunteers: t
View:

• Their age\< 35 up to 50 years old

• Both sexes.

• Controlled HTN ( stage 1,B.P 140-159 mmhg / 90-99 mmhg and stage 2, B.P 160-179 mmhg-100-109 mmhg )

• Hemodynamic stable. Able to provide informed consent

Locations
Other Locations
Egypt
Waleed Mohamed Abdelmohsen Abdelsalalm
RECRUITING
Minya
Time Frame
Start Date: 2025-07-10
Estimated Completion Date: 2026-01-01
Participants
Target number of participants: 20
Treatments
Experimental: DASH diet group
22 patients will receive hypotensive drugs and High Intensity Interval Training ( HIIT) combined with DASH diet.
Active_comparator: Comparator group
22 patients will receive hypotensive drugs and High Intensity Interval Training ( HIIT)
Related Therapeutic Areas
Sponsors
Leads: Deraya University

This content was sourced from clinicaltrials.gov

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