Evaluating Raised Intracranial Pressure Using MR Elastography
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test, Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Investigators will compare magnetic resonance (MR) elastography measurements to other forms of noninvasive methods of detecting raised intracranial pressure, including optical coherence tomography (OCT) imaging measurements of the retinal nerve fiber layer (RNFL) and indirect signs of raised intracranial pressure on magnetic resonance imaging (MRI).
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:
• Group 1: Papilledema from idiopathic intracranial hypertension and other forms of elevated intracranial pressure, including obstructive hydrocephalus
• Group 2: Patients without raised intracranial pressure.
Locations
United States
Minnesota
Mayo Clinic in Rochester
RECRUITING
Rochester
Contact Information
Primary
John J. Chen, M.D., Ph.D.
chen.john@mayo.edu
507-284-7140
Backup
Jacqueline A. Leavitt, M.D.
leavitt.jacqueline@mayo.edu
507-284-6263
Time Frame
Start Date: 2017-01-10
Estimated Completion Date: 2025-12
Participants
Target number of participants: 200
Treatments
Experimental: Patients with increased intracranial hypertension
Patients will receive the MR elastography, MRI structural brain imaging, Optical Coherence Tomography (OCT) imaging, Optic nerve B-scan ultrasound and Lumbar puncture.
Experimental: Patient without raised intracranial hypertension
Patients will receive the MR elastography, MRI structural brain imaging, Optical Coherence Tomography (OCT) imaging, and Optic nerve B-scan ultrasound. Some patients will receive lumbar punctures.
Related Therapeutic Areas
Sponsors
Leads: Mayo Clinic
Collaborators: National Eye Institute (NEI)