Three-dimensional MR Elastography and Two-dimensional MR Elastography for Assessing Cirrhosis and Portal Hypertension:A Prospective Multicenter Study
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Observational
SUMMARY
How to construct a novel, non-invasive, accurate, and convenient method to achieve prediction of hepatic venous pressure gradient (HVPG) is an important general problem in the management of portal hypertension in cirrhosis. We plan to compare the ability of three demensional-magnetic resonance elastography (3D-MRE) to two demensional-magnetic resonance elastography (2D-MRE) to establish a risk stratification system and perform tailored management for portal hypertension in cirrhosis.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:
• age \> 18 years old
• confirmed cirrhosis (laboratory, imaging and clinical symptoms)
• with 3D-MRE and 2D-MRE within 1 month prior to HVPG measurement
• written informed consent
Locations
Other Locations
China
Shengjing Hospital of China Medical University
RECRUITING
Shenyang
Contact Information
Primary
Yu Shi
18940259980@163.com
Backup
Zhiying Wang
wangzhiying990816@163.com
Time Frame
Start Date: 2022-08-16
Estimated Completion Date: 2025-12-01
Participants
Target number of participants: 100
Treatments
Experimental group
Experimental group was set to develop the novel non-invasive model for virtual HVPG using 3d-MRE
Control group
Control group was set to develop the novel non-invasive model for virtual HVPG using 2d-MRE
Related Therapeutic Areas
Sponsors
Leads: Shengjing Hospital