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The Efficacy of High-Power Laser Therapy as an Adjunct to Conservative Management in Patients With Meralgia Paresthetica: A Randomized, Assessor-Blinded, Controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Other, Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The management of MP typically follows a conservative pathway, encompassing patient education, lifestyle modifications (e.g., avoidance of tight garments, weight loss), pharmacotherapy (such as neuropathic pain agents or corticosteroid injections), and physical therapy. However, evidence supporting the efficacy of these interventions is largely anecdotal or derived from low-quality studies, and a substantial proportion of patients experience persistent symptoms refractory to standard care. Therefore, the primary objective of this randomized, sham-controlled, assessor-blinded study is to investigate the efficacy of HPLT as an adjunct to standard conservative care on pain intensity, sensory symptoms, and functional capacity in patients with chronic Meralgia Paresthetica. The investigators hypothesize that patients receiving active HPLT will demonstrate significantly greater improvements in these outcomes compared to those receiving a sham laser procedure

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:

• Adults aged 18-65 years.

• Clinical diagnosis of MP (based on history: burning pain, tingling, numbness in the lateral thigh; tenderness over the inguinal ligament near the anterior superior iliac spine (ASIS); and a positive pelvic compression test or Tinel's sign over the lateral femoral cutaneous nerve (LFCN)).

• Symptoms persistent for at least 3 months (chronic).

• A baseline pain intensity of ≥4 on the Numeric Rating Scale (NRS).

Locations
Other Locations
Turkey
Usak University
RECRUITING
Uşak
Contact Information
Primary
Ali Y Karahan, Prof.
ali.karahan@usak.edu.tr
+9053869219134
Backup
Ender Salbas, Asst. Prof.
drendersalbas@gmail.com
+905556698639
Time Frame
Start Date: 2026-01-12
Estimated Completion Date: 2026-08-05
Participants
Target number of participants: 50
Treatments
Experimental: Experimental Group: HPLT
Application Technique: Scanning technique. The laser probe will be moved slowly and continuously over the entire course of the LFCN (from just medial and inferior to the ASIS, distally along the thigh).
Sham_comparator: Control Group: Sham Laser
Identical procedure as Group 1, but with a sham laser applicator that emits no therapeutic energy. The device will beep and display as if it is working.
Sponsors
Collaborators: Balikesir University
Leads: Uşak University

This content was sourced from clinicaltrials.gov

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