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Presence of Neuropathic Pain in Knee Osteoarthritis: Relationship Between Pain Severity and Functional Status

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

Osteoarthritis (OA) is a degenerative joint disease characterized by structural changes such as cartilage loss and osteophyte formation, leading to functional limitations and disability. Pain in knee OA involves a complex pathophysiological structure including both nociceptive and neuropathic mechanisms. Identifying the neuropathic pain component is clinically significant for improving quality of life and functional recovery. This cross-sectional controlled clinical study aims to determine the prevalence of neuropathic pain in patients with knee OA and evaluate its impact on pain severity and functional status. Patients will be categorized based on the Douleur Neuropathique 4 (DN4) questionnaire and assessed using various pain and functional scales.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Maximum Age: 70
Healthy Volunteers: f
View:

• Diagnosed with Knee OA according to ACR criteria.

• Knee pain for more than 3 months.

• Voluntary participation.

Locations
Other Locations
Turkey
Istanbul Physical Medicine and Rehabilitation Training and Research Hospital
RECRUITING
Istanbul
Contact Information
Primary
Eser Kalaoglu, M.D.
eserkalaoglu@hotmail.com
+90 (212) 496 50 00
Time Frame
Start Date: 2025-12-20
Estimated Completion Date: 2026-04-30
Participants
Target number of participants: 102
Treatments
Group 1 (Case)
Patients with Knee OA and Neuropathic Pain (DN4 score ≥ 4)
Group 2 (Control)
Patients with Knee OA without Neuropathic Pain (DN4 score \< 4)
Related Therapeutic Areas
Sponsors
Leads: Istanbul Physical Medicine Rehabilitation Training and Research Hospital

This content was sourced from clinicaltrials.gov