Effects of Individualized Positive End-expiratory Pressure Guided by Driving Pressure on Postoperative Atelectasis After Bariatric Surgery in Patients With Morbid Obesity: A Single-center, Prospective, Randomized Controlled Study
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Atelectasis is a common complication in patients undergoing surgery under general anesthesia, particularly in obese patients. Postoperative atelectasis could last for more than 24h and contribute to a variety of other complications, including hypoxemia and pneumonia. We plan to conduct a single-center, randomized controlled trial in patients undergoing bariatric surgery to test the hypothesis that driving pressure guided PEEP could reduce the postoperative atelectasis.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 60
Healthy Volunteers: f
View:
• Age 18 to 60 years old;
• Body mass index (BMI) ≥ 40 kg/m2;
• ASA classification I to III;
• Signing the informed consent form for this clinical study;
Locations
Other Locations
China
Qianfoshan Hospital, The First Hospital affiliated of Shandong First Medical University
RECRUITING
Jinan
Contact Information
Primary
yong t Sun, Ph.D
sunyongtao1979@163.com
18660795201
Time Frame
Start Date: 2024-03-01
Estimated Completion Date: 2024-12-31
Participants
Target number of participants: 52
Treatments
Experimental: Individualized PEEP group
After recruitment maneuver, PEEP is titrated decreasingly using driving pressure guided individualised PEEP ventilation strategy, and the PEEP corresponding to the lowest driving pressure is the individualised PEEP.
Other: Fixed PEEP group
After recruitment maneuver, PEEP is fixed at 8cmH2O.
Related Therapeutic Areas
Sponsors
Leads: Yongtao Sun