A Prospective Multicenter Study to Determine the Usefulness of Systematic 18-FDG-PET-TC for the Management of Invasive Fungal Infection (PETIFI Project)

Status: Recruiting
Location: See all (14) locations...
Intervention Type: Procedure
Study Type: Observational
SUMMARY

The goal of this national multicenter prospective cohort study is to learn about the added value of 18F-FDG (18F-2-fluoro-2-deoxy-D-glucose) PET-CT in invasive fungal disease management. The main questions it aims to answer are: 1. Does the use of 18F-FDG PET-CT allow a better characterization of invasive fungal infection (IFI) (performance) compared to the exclusive use of conventional radiological studies in terms of extension/staging and monitoring of response/follow-up ? 2. Does the systematic and protocolized use of 18F-FDG PET-CT in IFI allow a better management of patients with IFI and increase the prognostic value of the initial evaluation? Participants will undergo systematically a 18F-FDG PET-CT as part of the work-up of their invasive fungal disease. Researchers will compare the performance of 18F-FDG PET-CT with standard management without 18F-FDG PET-CT to see if adds value (diagnostic, prognostic, and changes in management).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
View:

• 18-year-old adult patients

• who are admitted with a diagnosis of invasive fungal infection

• who able to undergo a one 18F-FDG PET-CT

• who give their informed consent.

Locations
Other Locations
Spain
Hospital de Bellvitge
RECRUITING
Barcelona
Hospital Universitario Clinic
RECRUITING
Barcelona
Hospital Universitario Virgen de las Nieves
RECRUITING
Granada
Hospital Infanta Leonor Hospital
RECRUITING
Madrid
Hospital Universitario Gregorio Marañón
RECRUITING
Madrid
Hospital Universitario La Paz
RECRUITING
Madrid
Hospital Unversitario Ramón y Cajal
RECRUITING
Madrid
Hospital Universitario Puerta de Hierro
RECRUITING
Majadahonda
Hospital Virgen de la Victoria
RECRUITING
Málaga
Hospital Morales Messeguer
NOT_YET_RECRUITING
Murcia
Hospital Virgen de la Arrixaca
NOT_YET_RECRUITING
Murcia
Hospital Universitario Central de Asturias
RECRUITING
Oviedo
Hospital Unversitario de Salamanca
RECRUITING
Salamanca
Hospital Universitario Virgenn de la Macarena
RECRUITING
Seville
Contact Information
Primary
Andrea Gutiérrez Villanueva, MD
a.gutierrezv@hotmail.com
+34618157518
Backup
Begoña Rodríguez Alfonso, MDPhD
brodrigueza@salud.madrid.org
+34630078311
Time Frame
Start Date: 2023-04-27
Estimated Completion Date: 2024-12-01
Participants
Target number of participants: 224
Related Therapeutic Areas
Sponsors
Leads: Puerta de Hierro University Hospital
Collaborators: Gilead Sciences

This content was sourced from clinicaltrials.gov

Similar Clinical Trials